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9 items tagged with 'metabolism'.
Assays (1)
ID: 72
Biological problem addressed: Metabolic network
Investigation: Investigation: Glucose metabolism in the liver
Contributor: Matthias König
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., A3.4: Linking signalling to metabolic functions
Organisms: Not Specified
SOPs: No SOPs
Data files: No Data files
Data files (1)
Uploader: Clemens Kreutz
Contributor: Clemens Kreutz, María Matilde Bartolomé Rodríguez
Other contributors: Not specified
Version: 1
Projects: A2.5: Integration of insulin and Wnt signalling in hepatocytes, A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato...
Scales: Cell
The data set was generated from four samples (mice). For each sample, three conditions were measured:
a) unsorted cells
b) sorted cells: low insulin binding type
c) sorted cells: high insuin binding type
Altogether, 4x3 =12 experimental data sets were investigated.
Gene expression profiling was performed using an AffymetrixGeneChip mouse gene 2.0 ST Array (Affymetrix Europe, Wooburn Green, UK).
The probe sequences can be downloaded from the Affymetrix website.
The following files contain probe
...
Created: 27th Mar 2014 at 09:06 Last updated: 26th Jan 2015 at 18:08
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Download Publications (5)
Authors: J Schleicher, R Guthke, U Dahmen, O Dirsch, H G Holzhuetter, S Schuster
PubMed ID: 23999488
Date Published: 4th Sep 2013
Projects: A3.6: Transcription factor network and links to metabolism in NAFLD
Journal: Biochim. Biophys. Acta
Citation: Biochim. Biophys. Acta 1841(1): 62-69
Scales: Cell
Abstract (Expand)
Created: 23rd Oct 2013 at 14:55 Last updated: 24th Oct 2013 at 16:14
Authors: Andreas Dräger, Hannes Planatscher
DOI: 10.1007/978-1-4419-9863-7_1277
Date Published: 2013
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes
Book: Encyclopedia of Systems Biology
Citation: Encyclopedia of Systems Biology : 1249
Scales: Cell
Abstract (Expand)
Created: 15th Aug 2013 at 23:34 Last updated: 23rd Jul 2015 at 13:38
Authors: Emanuel Gonçalves, Joachim Bucher, Anke Ryll, Jens Niklas, Klaus Mauch, Steffen Klamt, Miguel Rocha, Julio Saez-Rodriguez
PubMed ID: 23525368
Date Published: 26th Mar 2013
Projects: A2.5: Integration of insulin and Wnt signalling in hepatocytes, A3.4: Linking signalling to metabolic functions, A3.6: Transcription factor network and links to metabolism in NAFLD, A: Cellular level, E: Model integration, Virtual Liver
Journal: Mol Biosyst
Citation: Mol Biosyst 9(7): 1576-83
Scales: Cell, Liver and Organism
Abstract (Expand)
Created: 3rd Jun 2013 at 16:37 Last updated: 24th Oct 2013 at 16:14
Authors: Andreas Hoppe, Iryna Ilkavets, Steven Dooley, Hermann-Georg Holzhütter
Date Published: 1st Dec 2012
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., B2.3: Effect of hepatic stellate cells on hepatocyte polarity and transd...
Journal: Metabolites
Citation: Metabolites 2(4) : 983
Authors: M. Koenig, H.-G. Holzhuetter
Date Published: 12th Sep 2012
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., A1: Cellular metabolism, A3.4: Linking signalling to metabolic functions
Journal: Journal of Biological Chemistry
Citation: Journal of Biological Chemistry 287(44) : 36978
Abstract (Expand)
Created: 4th Oct 2012 at 18:18 Last updated: 24th Oct 2013 at 16:15
Presentations (2)
Uploader: Lars Ole Schwen
Contributor: Lars Ole Schwen, Matthias König, Tobias Preusser
Other contributors: Not specified
Version: 1
Projects: C1: The role of blood flow in liver lobule function and morphology, D1: Regulation of Blood Flow and Perfusion in the Liver, E3: Horizontal integration on organ scale, E4: Vertical integration across biological scales, Showcase Steatosis
Scales: Cell, Liver lobule, Liver and Organism
Presentation at WCCM-ECCM-ECFD 2014
Created: 25th Jul 2014 at 16:01
Uploader: Matthias König
Contributor: Hermann-Georg Holzhütter, Matthias König
Other contributors: Not specified
Version: 1
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., C1: The role of blood flow in liver lobule function and morphology, C2: Organization of the sinusoidal system and the liver lobule - referen..., C3: Zonation of metabolism and its regulation
Scales: Cell and Liver lobule
Overview preliminary results and first version of multi-scale model of human hepatic galactose metabolism.
First simulations of normal state and galactosemias.
See also:
Galactose investigation
http://seek.virtuelle-leber.de/investigations/88
Galactose study
http://seek.virtuelle-leber.de/studies/50
Galactose modelling assay
http://seek.virtuelle-leber.de/assays/71
Created: 3rd Nov 2013 at 15:03 Last updated: 8th Nov 2013 at 11:10
