Virtual Liver SEEK

4 items tagged with 'ODE'.

Publications (4)

SBMLsqueezer 2: context-sensitive creation of kinetic equations in biochemical networks

Authors: Andreas Dräger, Daniel C Zielinski, Roland Keller, Matthias Rall, Johannes Eichner, Bernhard O Palsson, Andreas Zell

DOI: 10.1186/s12918-015-0212-9

Date Published: 1st Dec 2015

Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes

Journal: BMC Syst Biol

Citation: BMC Syst Biol 9(1) : 389

Scales: Cell and Intercellular

Abstract (Expand)

Background: The size and complexity of published biochemical network reconstructions are steadily increasing, expanding the potential scale of derived computational models. However, the construction ...

Created: 16th Nov 2015 at 15:27 Last updated: 16th Nov 2015 at 15:29

Computational prediction of molecular pathogen-host interactions based on dual transcriptome data

Authors: Sylvie Schulze, Sebastian G. Henkel, Dominik Driesch, Reinhard Guthke, JÃ¶rg Linde

DOI: 10.3389/fmicb.2015.00065

Date Published: 6th Feb 2015

Projects: Virtual Liver

Journal: Front. Microbiol.

Citation: Front. Microbiol. 6

Scales: Cell and Intercellular

Abstract:

Not specified

Created: 11th Feb 2015 at 08:18 Last updated: 11th Feb 2015 at 08:24

The systems biology simulation core algorithm

Authors: Roland Keller, Alexander Dörr, Akito Tabira, Akira Funahashi, Michael J Ziller, Richard Adams, Nicolas Rodriguez, Nicolas Le Novère, Noriko Hiroi, Hannes Planatscher, Andreas Zell, Andreas Dräger

DOI: 10.1186/1752-0509-7-55

Date Published: 2013

Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes

Journal: BMC Syst Biol

Citation: BMC Syst Biol 7(1) : 55

Scales: Cell, Intercellular, Liver lobule, Liver and Organism

Abstract (Expand)

Background With the increasing availability of high dimensional time course data for metabolites, genes, and fluxes, the mathematical description of dynamical systems has become an essential aspect of ...

Created: 9th Jul 2013 at 04:12 Last updated: 24th Oct 2013 at 16:15

Inference of dynamical gene-regulatory networks based on time-resolved multi-stimuli multi-experiment data applying NetGenerator V2.0

Authors: Michael Weber, Sebastian G Henkel, Sebastian Vlaic, Reinhard Guthke, Everardus J van Zoelen, Dominik Driesch

DOI: 10.1186/1752-0509-7-1

Date Published: 2013

Projects: Virtual Liver

Journal: BMC Syst Biol

Citation: BMC Syst Biol 7(1) : 1

Scales: Not specified

Abstract (Expand)

BACKGROUND Inference of gene-regulatory networks (GRNs) is important for understanding behaviour and potential treatment of biological systems. Knowledge about GRNs gained from transcriptome analysis ...

Created: 2nd Jan 2013 at 10:24 Last updated: 24th Oct 2013 at 16:15