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Publications (6)
Expression variability of absorption, distribution, metabolism, excretion-related microRNAs in human liver: influence of nongenetic factors and association with gene expression
Authors: Jessica K Rieger, Kathrin Klein, Stefan Winter, Ulrich M Zanger
PubMed ID: 23733276
Date Published: 3rd Jun 2013
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes
Journal: Drug Metab. Dispos.
Citation: Drug Metab. Dispos. 41(10): 1752-62
Scales: Not specified
Abstract (Expand)
Created: 8th Jan 2014 at 14:05
Authors: Kathrin Klein, Stefan Winter, Miia Turpeinen, Matthias Schwab, Ulrich M. Zanger
Date Published: 2010
Projects: B5: Cell-cell communication influences detoxifying functions in hepatocytes
Journal: Front. Pharmacol.
Citation: Front. Pharmacol. 1
Scales: Not specified
Abstract (Expand)
Created: 27th Jan 2011 at 14:52  Last updated: 24th Oct 2013 at 16:20
Transcriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery disease
Authors: Yijing Zhang, Kathrin Klein, Aarathi Sugathan, Najlla Nassery, Alan Dombkowski, Ulrich M Zanger, David J Waxman
PubMed ID: 21858147
Date Published: 12th Aug 2011
Projects: A3.4: Linking signalling to metabolic functions
Journal: PLoS ONE
Citation: PLoS ONE 6(8): e23506
Scales: Not specified
Abstract (Expand)
Created: 14th May 2012 at 09:54  Last updated: 24th Oct 2013 at 16:17
DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma
Authors: Elke Schaeffeler, Claus Hellerbrand, Anne T Nies, Stefan Winter, Stephan Kruck, Ute Hofmann, Heiko van der Kuip, Ulrich M Zanger, Hermann Koepsell, Matthias Schwab
PubMed ID: 22196450
Date Published: 23rd Dec 2011
Projects: C3: Zonation of metabolism and its regulation, G1: Clinical Translation to Invasively Characterized Patients, G2: Clinical Translation to Non-Invasive Volunteer Setting, G3: Clinical Translation to Pharmaceutical Drug Development, G4: Whole-Body Detoxification in Mouse Models
Journal: Genome Med
Citation: Genome Med 3(12): 82
Scales: Cell
Abstract (Expand)
Created: 27th Jun 2012 at 15:59  Last updated: 24th Oct 2013 at 16:17
Authors: Kathrin Klein, Maria Thomas, Stefan Winter, Andreas K Nussler, Mikko Niemi, Matthias Schwab, Ulrich M Zanger
PubMed ID: 22510778
Date Published: 18th Apr 2012
Projects: A3.4: Linking signalling to metabolic functions
Journal: Clinical pharmacology and therapeutics
Citation: Clin. Pharmacol. Ther. 91(6): 1044-52
Scales: Not specified
Abstract (Expand)
Created: 14th May 2012 at 09:40  Last updated: 24th Oct 2013 at 16:16
Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver
Authors: A Schröder, K Klein, S Winter, M Schwab, M Bonin, A Zell, U M Zanger
PubMed ID: 22006096
Date Published: 18th Oct 2011
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions, A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes, C3: Zonation of metabolism and its regulation, G1: Clinical Translation to Invasively Characterized Patients, G2: Clinical Translation to Non-Invasive Volunteer Setting, G3: Clinical Translation to Pharmaceutical Drug Development, G4: Whole-Body Detoxification in Mouse Models
Journal: Not specified
Citation: Pharmacogenomics J. 13(1): 12-20
Scales: Not specified
Abstract (Expand)
Created: 3rd Nov 2011 at 10:45  Last updated: 24th Oct 2013 at 16:17