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Publications (121)
Authors: A Raue, C Kreutz, T Maiwald, U Klingmuller, J Timmer
PubMed ID: 21405200
Date Published: 17th Mar 2011
Projects: A2.1: Multi-level regulation of signalling pathways important for primin..., A2.3: Cross-talk and distinct properties of growth factor signalling reg..., A2.5: Integration of insulin and Wnt signalling in hepatocytes, B2.1: Hepatic stellate cells as source and target for hepatocellular gro...
Journal: IET Syst Biol
Citation: IET Syst Biol 5(2): 120-30
Scales: Cell and Intercellular
Abstract (Expand)
Created: 18th Jul 2012 at 09:24  Last updated: 24th Oct 2013 at 16:18
Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions
Authors: Katrin Luckert, Frank Götschel, Peter K Sorger, Andreas Hecht, Thomas O Joos, Oliver Pötz
PubMed ID: 21378377
Date Published: 4th Mar 2011
Projects: A2.5: Integration of insulin and Wnt signalling in hepatocytes, B2.2: Importance of Wnt- and Hedgehog factors for hepatic stellate cells...
Journal: Mol. Cell Proteomics
Citation: Mol. Cell Proteomics 10(5): M110.007377
Scales: Cell
Abstract (Expand)
Created: 13th Sep 2012 at 13:58  Last updated: 24th Oct 2013 at 16:19
Authors: Mirco Castoldi, Maja Vujic Spasic, Sandro Altamura, Joacim Elmén, Morten Lindow, Judit Kiss, Jens Stolte, Richard Sparla, Lorenza A D'Alessandro, Ursula Klingmüller, Robert E Fleming, Thomas Longerich, Hermann J Gröne, Vladimir Benes, Sakari Kauppinen, Matthias W Hentze, Martina U Muckenthaler
PubMed ID: 21364282
Date Published: 3rd Mar 2011
Projects: B1.3: Linking modulation of iron metabolism with the impact of macrophag...
Journal: J. Clin. Invest.
Citation: J. Clin. Invest. 121(4): 1386-96
Scales: Cell, Liver and Organism
Abstract (Expand)
Created: 11th Jul 2012 at 10:47  Last updated: 24th Oct 2013 at 16:19
Authors: M Schwab, E Schaeffeler, U M Zanger, H Brauch, H K Kroemer
PubMed ID: 21365522
Date Published: 1st Mar 2011
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes, G2: Clinical Translation to Non-Invasive Volunteer Setting
Journal: Dtsch. Med. Wochenschr.
Citation: Dtsch. Med. Wochenschr. 136(10): 461-7
Scales: Cell
Abstract (Expand)
Created: 27th Jun 2012 at 16:14  Last updated: 24th Oct 2013 at 16:19
Authors: L T Joeckel, R Wallich, P Martin, D Sanchez-Martinez, F C Weber, S F Martin, C Borner, J Pardo, C Froelich, M M Simon
PubMed ID: 21311565
Date Published: 11th Feb 2011
Projects: No Projects
Journal: Cell Death Differ.
Citation: Cell Death Differ. 18(7): 1112-9
Scales: Not specified
Abstract (Expand)
Created: 22nd Jan 2014 at 15:28
ABCB1 single-nucleotide polymorphisms determine tacrolimus response in patients with ulcerative colitis
Authors: K R Herrlinger, H Koc, S Winter, A Teml, E F Stange, K Fellermann, P Fritz, M Schwab, E Schaeffeler
PubMed ID: 21289623
Date Published: 2nd Feb 2011
Projects: G2: Clinical Translation to Non-Invasive Volunteer Setting
Journal: Clin. Pharmacol. Ther.
Citation: Clin. Pharmacol. Ther. 89(3): 422-8
Scales: Not specified
Abstract (Expand)
Created: 18th Jul 2012 at 12:30  Last updated: 24th Oct 2013 at 16:19
The influence of the chloride currents on action potential firing and volume regulation of excitable cells studied by a kinetic model
Authors: Nikolaus Berndt, Sabrina Hoffmann, Jan Benda, Hermann-Georg Holzhütter
PubMed ID: 21295041
Date Published: 2nd Feb 2011
Projects: No Projects
Journal: J. Theor. Biol.
Citation: J. Theor. Biol. 276(1): 42-9
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 11:22  Last updated: 24th Oct 2013 at 16:19
Authors: Christa Buechler, Thomas S Weiss
PubMed ID: 21222589
Date Published: 13th Jan 2011
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions, A2: Integration of Signalling Pathways in Hepatocellular Response
Journal: Curr. Drug Metab.
Citation: Curr. Drug Metab. 12(1): 24-34
Authors: A Raue, V Becker, U Klingmüller, J Timmer
PubMed ID: 21198117
Date Published: 5th Jan 2011
Projects: A2: Integration of Signalling Pathways in Hepatocellular Response
Journal: Chaos
Citation: Chaos 20(4): 045105
Scales: Cell
Abstract (Expand)
Created: 10th Aug 2012 at 09:43  Last updated: 24th Oct 2013 at 16:19
Authors: André Homeyer, Uta Dahmen, Hai Huang, Andrea Schenk, Olaf Dirsch, HorstK Hahn
Date Published: 2011
Projects: D4: Regeneration and Liver Size
Journal: J Pathol Inform
Citation: J Pathol Inform 2(2) : 11
Scales: Liver
Abstract (Expand)
Created: 9th Mar 2012 at 15:42  Last updated: 24th Oct 2013 at 16:19
Authors: Beate Fuchs, Rosmarie Süss, Kristin Teuber, Mandy Eibisch, Jürgen Schiller
PubMed ID: 21167493
Date Published: 14th Oct 2010
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: J Chromatogr A
Citation: J Chromatogr A 1218(19): 2754-74
Scales: Not specified
Abstract (Expand)
Created: 23rd Jun 2011 at 17:18  Last updated: 24th Oct 2013 at 16:19
HMMerThread: detecting remote, functional conserved domains in entire genomes by combining relaxed sequence-database searches with fold recognition
Authors: Charles Richard Bradshaw, Vineeth Surendranath, Robert Henschel, Matthias Stefan Mueller, Bianca Hermine Habermann
PubMed ID: 21423752
Date Published: 16th Nov 2010
Projects: A1.3: Identification of crucial metabolic processes during hepatocyte pr..., A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato..., A3.5: The impact of cell polarity on metabolism detoxification and endoc..., C2: Organization of the sinusoidal system and the liver lobule - referen..., C5: Structural changes and functional consequences of the liver lobular/..., C6: Organization and function of the sinusoidal system and the liver lob...
Journal: PLoS ONE
Citation: PLoS ONE 6(3): e17568
Scales: Not specified
Abstract (Expand)
Created: 24th Jun 2011 at 16:19  Last updated: 24th Oct 2013 at 16:19
Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets
Authors: Valentina Raia, Marcel Schilling, Martin Böhm, Bettina Hahn, Andreas Kowarsch, Andreas Raue, Carsten Sticht, Sebastian Bohl, Maria Saile, Peter Möller, Norbert Gretz, Jens Timmer, Fabian Theis, Wolf-Dieter Lehmann, Peter Lichter, Ursula Klingmüller
PubMed ID: 21127196
Date Published: 2nd Dec 2010
Scales: Not specified
Abstract (Expand)
Created: 10th Aug 2012 at 09:41  Last updated: 24th Oct 2013 at 16:19
Sphingomyelin is more sensitively detectable as a negative ion than phosphatidylcholine: a matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study using 9-aminoacridine (9-AA) as matrix
Authors: Mandy Eibisch, Jürgen Schiller
PubMed ID: 21452388
Date Published: 15th Dec 2010
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: Rapid Commun. Mass Spectrom.
Citation: Rapid Commun. Mass Spectrom. 25(8): 1100-6
Scales: Not specified
Abstract (Expand)
Created: 23rd Jun 2011 at 17:22  Last updated: 24th Oct 2013 at 16:19
Automated extraction of DNA and RNA from a single formalin-fixed paraffin-embedded tissue section for analysis of both single-nucleotide polymorphisms and mRNA expression
Authors: Guido Hennig, Mathias Gehrmann, Udo Stropp, Hiltrud Brauch, Peter Fritz, Michel Eichelbaum, Matthias Schwab, Werner Schroth
PubMed ID: 20947696
Date Published: 14th Oct 2010
Projects: No Projects
Journal: Clin. Chem.
Citation: Clin. Chem. 56(12): 1845-53
Scales: Not specified
Abstract (Expand)
Created: 18th Jul 2012 at 12:20  Last updated: 24th Oct 2013 at 16:19
Authors: Elke Ueberham, Jan Böttger, Uwe Ueberham, Jens Grosche, Rolf Gebhardt
PubMed ID: 20942944
Date Published: 13th Oct 2010
Projects: A: Cellular level, B: Communication of Hepatocytes and Non-Parenchymal Liver Cells, C: Liver lobule level
Journal: Comp Hepatol
Citation: Comp Hepatol 9: 8
Scales: Cell, Intercellular, Liver lobule and Liver
Abstract (Expand)
Created: 20th Jul 2012 at 10:16  Last updated: 24th Oct 2013 at 16:19
Authors: Rebekka Schlatter, Kathrin Schmich, Anna Lutz, Judith Trefzger, Oliver Sawodny, Michael Ederer, Irmgard Merfort
PubMed ID: 21533085
Date Published: 7th Oct 2010
Projects: A2.2: Regulation of pro-apoptotic and anti-apoptotic responses in hepato...
Journal: PLoS ONE
Citation: PLoS ONE 6(4): e18646
Scales: Cell
Abstract (Expand)
Created: 12th May 2011 at 15:13  Last updated: 24th Oct 2013 at 16:19
Phenotype and growth behavior of residual β-catenin-positive hepatocytes in livers of β-catenin-deficient mice
Authors: Albert Braeuning, Yasmin Singh, Benjamin Rignall, Albrecht Buchmann, Seddik Hammad, Amnah Othman, Iris von Recklinghausen, Patricio Godoy, Stefan Hoehme, Dirk Drasdo, Jan G Hengstler, Michael Schwarz
PubMed ID: 20886225
Date Published: 1st Oct 2010
Projects: No Projects
Journal: Histochem. Cell Biol.
Citation: Histochem. Cell Biol. 134(5): 469-81
Scales: Not specified
Abstract (Expand)
Created: 10th Sep 2012 at 17:18  Last updated: 24th Oct 2013 at 16:19
Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner
Authors: Kathrin Schmich, Rebekka Schlatter, Nadia Corazza, Karine Sá Ferreira, Michael Ederer, Thomas Brunner, Christoph Borner, Irmgard Merfort
PubMed ID: 20872776
Date Published: 24th Sep 2010
Projects: A2.2: Regulation of pro-apoptotic and anti-apoptotic responses in hepato...
Journal: Hepatology
Citation: Hepatology 53(1): 282-92
Scales: Cell and Intercellular
Abstract (Expand)
Created: 16th Jul 2012 at 16:53  Last updated: 24th Oct 2013 at 16:19
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis
Authors: Carola Huthmacher, Andreas Hoppe, Sascha Bulik, Hermann-Georg Holzhütter
PubMed ID: 20807400
Date Published: 31st Aug 2010
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: BMC Syst Biol
Citation: BMC Syst Biol 4: 120
Scales: Cell
Abstract (Expand)
Created: 4th Jan 2013 at 10:50  Last updated: 24th Oct 2013 at 16:19
Authors: Stefan Hoehme, Dirk Drasdo
PubMed ID: 20709692
Date Published: 13th Aug 2010
Projects: No Projects
Journal: Bioinformatics
Citation: Bioinformatics 26(20): 2641-2
Scales: Not specified
Abstract (Expand)
Created: 10th Sep 2012 at 17:45  Last updated: 24th Oct 2013 at 16:19
Authors: Bruno Galy, Dunja Ferring-Appel, Sven W Sauer, Sylvia Kaden, Saïd Lyoumi, Herve Puy, Stefan Kölker, Hermann-Josef Gröne, Matthias W Hentze
PubMed ID: 20674864
Date Published: 3rd Aug 2010
Projects: B1.3: Linking modulation of iron metabolism with the impact of macrophag..., HepatoSys
Journal: Cell Metab.
Citation: Cell Metab. 12(2): 194-201
Scales: Cell
Abstract (Expand)
Created: 29th Oct 2012 at 11:00  Last updated: 24th Oct 2013 at 16:20
Authors: Guoguang Sun, Dana Maria Rosu, Xin Zhang, Marc Hovestädt, Simona Pop, Ulrich Schade, Dennis Aulich, Michael Gensch, Bernhard Ay, Hermann-Georg Holzhütter, Dietrich R. T. Zahn, Norbert Esser, Rudolf Volkmer, Jörg Rappich, Karsten Hinrichs
Date Published: 1st Aug 2010
Projects: No Projects
Journal: phys. stat. sol. (b)
Citation: phys. stat. sol. (b) 247(8) : 1925
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 12:51  Last updated: 24th Oct 2013 at 16:20
Authors: Matthias W Hentze, Martina U Muckenthaler, Bruno Galy, Clara Camaschella
PubMed ID: 20603012
Date Published: 7th Jul 2010
Projects: B1.3: Linking modulation of iron metabolism with the impact of macrophag..., HepatoSys
Journal: Cell
Citation: Cell 142(1): 24-38
Scales: Cell
Abstract (Expand)
Created: 29th Oct 2012 at 11:04  Last updated: 24th Oct 2013 at 16:20
Authors: Matthias König, Hermann-Georg Holzhütter
PubMed ID: 22081592
Date Published: 1st Jul 2010
Projects: No Projects
Journal: Genome Inform
Citation: Genome Inform 24(1): 96-103
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 11:14  Last updated: 24th Oct 2013 at 16:20
Authors: Edda Klipp, Rebecca C Wade, Ursula Kummer
PubMed ID: 20554441
Date Published: 14th Jun 2010
Scales: Not specified
Abstract (Expand)
Created: 30th Aug 2012 at 13:17  Last updated: 24th Oct 2013 at 16:20
Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration
Authors: Stefan Hoehme, Marc Brulport, Alexander Bauer, Essam Bedawy, Wiebke Schormann, Matthias Hermes, Verena Puppe, Rolf Gebhardt, Sebastian Zellmer, Michael Schwarz, Ernesto Bockamp, Tobias Timmel, Jan G Hengstler, Dirk Drasdo
PubMed ID: 20484673
Date Published: 19th May 2010
Projects: B: Communication of Hepatocytes and Non-Parenchymal Liver Cells
Journal: Proc. Natl. Acad. Sci. U.S.A.
Citation: Proc. Natl. Acad. Sci. U.S.A. 107(23): 10371-6
Scales: Liver lobule
Abstract (Expand)
Created: 14th Aug 2012 at 08:44  Last updated: 24th Oct 2013 at 16:20
Authors: Beate Fuchs, Rosmarie Süss, Jürgen Schiller
PubMed ID: 20643161
Date Published: 25th Apr 2010
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: Prog. Lipid Res.
Citation: Prog. Lipid Res. 49(4): 450-75
Scales: Not specified
Abstract (Expand)
Created: 23rd Jun 2011 at 17:13  Last updated: 24th Oct 2013 at 16:20
Genome-wide comparison between IL-17 and combined TNF-alpha/IL-17 induced genes in primary murine hepatocytes
Authors: Titus Sparna, Julia Rétey, Kathrin Schmich, Ute Albrecht, Katrin Naumann, Norbert Gretz, Hans-Peter Fischer, Johannes G Bode, Irmgard Merfort
PubMed ID: 20374638
Date Published: 7th Apr 2010
Projects: A1.3: Identification of crucial metabolic processes during hepatocyte pr..., A2.2: Regulation of pro-apoptotic and anti-apoptotic responses in hepato..., A2.4: Linking signalling pathways regulating liver regeneration and orga..., A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato..., HepatoSys
Journal: BMC Genomics
Citation: BMC Genomics 11: 226
Scales: Cell
Abstract (Expand)
Created: 30th Aug 2012 at 12:22  Last updated: 24th Oct 2013 at 16:20
Authors: Peggy Stock, Sandra Brückner, Sabine Ebensing, Madlen Hempel, Matthias M Dollinger, Bruno Christ
PubMed ID: 20224562
Date Published: 11th Mar 2010
Projects: C6: Organization and function of the sinusoidal system and the liver lob...
Journal: Nat Protoc
Citation: Nat Protoc 5(4): 617-27
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
Authors: Yevhen Vainshtein, Mayka Sanchez, Alvis Brazma, Matthias W Hentze, Thomas Dandekar, Martina U Muckenthaler
PubMed ID: 20193060
Date Published: 1st Mar 2010
Scales: Not specified
Abstract (Expand)
Created: 30th Oct 2012 at 08:53  Last updated: 24th Oct 2013 at 16:20
Interpretation of non-invasive breath tests using (13)C-labeled substrates--a preliminary report with (13)C-methacetin
Authors: J F Lock, P Taheri, S Bauer, H-G Holzhütter, M Malinowski, P Neuhaus, M Stockmann
PubMed ID: 20149989
Date Published: 13th Feb 2010
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions
Journal: Eur. J. Med. Res.
Citation: Eur. J. Med. Res. 14: 547-50
Scales: Not specified
Abstract (Expand)
Created: 8th Jan 2013 at 11:53  Last updated: 24th Oct 2013 at 16:20
Authors: Kathrin Klein, Stefan Winter, Miia Turpeinen, Matthias Schwab, Ulrich M. Zanger
Date Published: 2010
Projects: B5: Cell-cell communication influences detoxifying functions in hepatocytes
Journal: Front. Pharmacol.
Citation: Front. Pharmacol. 1
Scales: Not specified
Abstract (Expand)
Created: 27th Jan 2011 at 14:52  Last updated: 24th Oct 2013 at 16:20
Authors: Katarzyna Mleczko-Sanecka, Guillem Casanovas, Anan Ragab, Katja Breitkopf, Alexandra Müller, Michael Boutros, Steven Dooley, Matthias W Hentze, Martina U Muckenthaler
PubMed ID: 20040761
Date Published: 29th Dec 2009
Projects: B1.3: Linking modulation of iron metabolism with the impact of macrophag...
Journal: Blood
Citation: Blood 115(13): 2657-65
Scales: Not specified
Abstract (Expand)
Created: 30th Oct 2012 at 08:51  Last updated: 24th Oct 2013 at 16:21
Authors: Matthias Stein, Razif R Gabdoulline, Rebecca C Wade
PubMed ID: 20024078
Date Published: 16th Dec 2009
Projects: F3: Kinetic data handling, HepatoSys
Journal: Mol Biosyst
Citation: Mol Biosyst 6(1): 152-64
Scales: Not specified
Abstract (Expand)
Created: 31st Oct 2012 at 14:08  Last updated: 24th Oct 2013 at 16:21
Authors: Hartmut Schlüter, Rolf Apweiler, Hermann-Georg Holzhütter, Peter R Jungblut
PubMed ID: 19740416
Date Published: 9th Sep 2009
Projects: No Projects
Journal: Chem Cent J
Citation: Chem Cent J 3: 11
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 12:56  Last updated: 24th Oct 2013 at 16:21
Authors: Irina Surovtsova, Natalia Simus, Thomas Lorenz, Artjom König, Sven Sahle, Ursula Kummer
PubMed ID: 19633098
Date Published: 24th Jul 2009
Scales: Not specified
Abstract (Expand)
Created: 30th Aug 2012 at 13:24  Last updated: 24th Oct 2013 at 16:21
Authors: Sabrina Hoffmann, Hermann-Georg Holzhütter
PubMed ID: 19348632
Date Published: 8th Apr 2009
Projects: No Projects
Journal: Ann. N. Y. Acad. Sci.
Citation: Ann. N. Y. Acad. Sci. 1158: 57-70
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 12:53  Last updated: 24th Oct 2013 at 16:21
Authors: Andreas Dräger, Hannes Planatscher, Dieudonné Motsou Wouamba, Adrian Schröder, Michael Hucka, Lukas Endler, Martin Golebiewski, Wolfgang Müller, Andreas Zell
PubMed ID: 19307240
Date Published: 23rd Mar 2009
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes, HepatoSys
Journal: Bioinformatics
Citation: Bioinformatics 25(11): 1455-6
Scales: Not specified
Abstract (Expand)
Created: 11th Jan 2011 at 11:11  Last updated: 24th Oct 2013 at 16:21
Authors: Iwona Wallach, Juan Zhang, Anika Hartmann, Frank K H van Landeghem, Anna Ivanova, Martin Klar, Christof Dame
PubMed ID: 19218878
Date Published: 17th Feb 2009
Projects: No Projects
Journal: Pediatr. Res.
Citation: Pediatr. Res. 65(6): 619-24
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 11:24  Last updated: 24th Oct 2013 at 16:21
Authors: Dawadschargal Bech-Otschir, Annett Helfrich, Cordula Enenkel, Gesa Consiglieri, Michael Seeger, Hermann-Georg Holzhütter, Burkhardt Dahlmann, Peter-Michael Kloetzel
PubMed ID: 19169257
Date Published: 25th Jan 2009
Projects: No Projects
Journal: Nat. Struct. Mol. Biol.
Citation: Nat. Struct. Mol. Biol. 16(2): 219-25
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 12:53  Last updated: 24th Oct 2013 at 16:21
Kinetic hybrid models composed of mechanistic and simplified enzymatic rate laws--a promising method for speeding up the kinetic modelling of complex metabolic networks
Authors: Sascha Bulik, Sergio Grimbs, Carola Huthmacher, Joachim Selbig, Hermann G Holzhütter
PubMed ID: 19137631
Date Published: 13th Jan 2009
Projects: No Projects
Journal: FEBS J.
Citation: FEBS J. 276(2): 410-24
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 11:06  Last updated: 24th Oct 2013 at 16:22
A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts
Authors: Nils Blüthgen, Stefan Legewie, Szymon M Kielbasa, Anja Schramme, Oleg Tchernitsa, Jana Keil, Andrea Solf, Martin Vingron, Reinhold Schäfer, Hanspeter Herzel, Christine Sers
PubMed ID: 19154344
Date Published: 12th Jan 2009
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 11:44  Last updated: 24th Oct 2013 at 16:22
Authors: Stefan Legewie, Christine Sers, Hanspeter Herzel
PubMed ID: 19059249
Date Published: 4th Dec 2008
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 12:56  Last updated: 24th Oct 2013 at 16:22
Authors: Dorothée Walter, Kathrin Schmich, Sandra Vogel, Robert Pick, Thomas Kaufmann, Florian Christoph Hochmuth, Angelika Haber, Karin Neubert, Sabine McNelly, Fritz von Weizsäcker, Irmgard Merfort, Ulrich Maurer, Andreas Strasser, Christoph Borner
PubMed ID: 19003879
Date Published: 13th Nov 2008
Scales: Cell
Abstract (Expand)
Created: 30th Aug 2012 at 12:31  Last updated: 24th Oct 2013 at 16:22
Authors: Marc Flajolet, Zhongfeng Wang, Marie Futter, Weixing Shen, Nina Nuangchamnong, Jacob Bendor, Iwona Wallach, Angus C Nairn, D James Surmeier, Paul Greengard
PubMed ID: 18953346
Date Published: 26th Oct 2008
Projects: No Projects
Journal: Nat. Neurosci.
Citation: Nat. Neurosci. 11(12): 1402-9
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 11:25  Last updated: 24th Oct 2013 at 16:22
Authors: Nils Blüthgen, Stefan Legewie
PubMed ID: 18793126
Date Published: 17th Sep 2008
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 12:58  Last updated: 24th Oct 2013 at 16:22
Authors: Peter R Jungblut, Hermann G Holzhütter, Rolf Apweiler, Hartmut Schlüter
PubMed ID: 18638390
Date Published: 18th Jul 2008
Projects: No Projects
Journal: Chem Cent J
Citation: Chem Cent J 2: 16
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 13:00  Last updated: 24th Oct 2013 at 16:22
Authors: Thomas Maiwald, Jens Timmer
PubMed ID: 18614583
Date Published: 9th Jul 2008
Scales: Not specified
Abstract (Expand)
Created: 17th Aug 2012 at 10:13  Last updated: 24th Oct 2013 at 16:22
Authors: Stefan Legewie, Dennis Dienst, Annegret Wilde, Hanspeter Herzel, Ilka M Axmann
PubMed ID: 18599624
Date Published: 3rd Jul 2008
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:00  Last updated: 24th Oct 2013 at 16:22
Authors: Ilka M Axmann, Stefan Legewie, Hanspeter Herzel
PubMed ID: 18546474
Date Published: 12th Jun 2008
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:01  Last updated: 24th Oct 2013 at 16:22
Authors: Katrin Hübner, Thomas Schwager, Karl Winkler, Jens-Georg Reich, Hermann-Georg Holzhütter
PubMed ID: 18497853
Date Published: 24th May 2008
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: PLoS Comput. Biol.
Citation: PLoS Comput. Biol. 4(5): e1000079
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 12:57  Last updated: 24th Oct 2013 at 16:22
Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network
Authors: Martina U Muckenthaler, Bruno Galy, Matthias W Hentze
PubMed ID: 18489257
Date Published: 21st May 2008
Scales: Cell
Abstract (Expand)
Created: 29th Oct 2012 at 11:06  Last updated: 24th Oct 2013 at 16:22
Authors: Stefan Legewie, Hanspeter Herzel, Hans V Westerhoff, Nils Blüthgen
PubMed ID: 18463614
Date Published: 6th May 2008
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:02  Last updated: 24th Oct 2013 at 16:22
Authors: Stefan Richter, Anne Wenzel, Matthias Stein, Razif R Gabdoulline, Rebecca C Wade
PubMed ID: 18420653
Date Published: 17th Apr 2008
Projects: No Projects
Journal: Nucleic Acids Res.
Citation: Nucleic Acids Res. 36(Web Server issue): W276-80
Scales: Not specified
Abstract (Expand)
Created: 31st Oct 2012 at 14:11  Last updated: 24th Oct 2013 at 16:22
Authors: Mark M Schatz, Björn Peters, Nadja Akkad, Nina Ullrich, Alejandra Nacarino Martinez, Oliver Carroll, Sascha Bulik, Hans-Georg Rammensee, Peter van Endert, Hermann-Georg Holzhütter, Stefan Tenzer, Hansjörg Schild
PubMed ID: 18292545
Date Published: 23rd Feb 2008
Projects: No Projects
Journal: J. Immunol.
Citation: J. Immunol. 180(5): 3210-7
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 11:07  Last updated: 24th Oct 2013 at 16:22
Modeling the in vitro 20S proteasome activity: the effect of PA28-alphabeta and of the sequence and length of polypeptides on the degradation kinetics
Authors: Michele Mishto, Fabio Luciani, Hermann-Georg Holzhütter, Elena Bellavista, Aurelia Santoro, Kathrin Textoris-Taube, Claudio Franceschi, Peter M Kloetzel, Alexey Zaikin
PubMed ID: 18336834
Date Published: 8th Feb 2008
Projects: No Projects
Journal: J. Mol. Biol.
Citation: J. Mol. Biol. 377(5): 1607-17
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 13:01  Last updated: 24th Oct 2013 at 16:22
Authors: Anuradha Chauhan, Stefan Legewie, Pål O Westermark, Stephan Lorenzen, Hanspeter Herzel
PubMed ID: 18339403
Date Published: 1st Feb 2008
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:05  Last updated: 24th Oct 2013 at 16:22
Authors: Matthias Stein, Razif R Gabdoulline, Rebecca C Wade
PubMed ID: 18208384
Date Published: 23rd Jan 2008
Scales: Cell
Abstract (Expand)
Created: 31st Oct 2012 at 14:12  Last updated: 24th Oct 2013 at 16:23
Authors: Chirstoph Gille, Andreas Hoppe, Herman-Georg Holzhütter
PubMed ID: 19425142
Date Published: 2008
Projects: F2: The Liver Knowledge Base (LKB)
Journal: Genome Inform
Citation: Genome Inform 20: 277-84
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 10:55  Last updated: 24th Oct 2013 at 16:23
Authors: Benjamin Sefa Menküc, Christoph Gille, Hermann-Georg Holzhütter
PubMed ID: 19425141
Date Published: 2008
Projects: No Projects
Journal: Genome Inform
Citation: Genome Inform 20: 270-6
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 13:01  Last updated: 24th Oct 2013 at 16:23
Inhibition of GSK3 differentially modulates NF-kappaB, CREB, AP-1 and beta-catenin signaling in hepatocytes, but fails to promote TNF-alpha-induced apoptosis
Authors: Frank Götschel, Claudia Kern, Simona Lang, Titus Sparna, Cordula Markmann, Joseph Schwager, Sabine McNelly, Fritz von Weizsäcker, Stefan Laufer, Andreas Hecht, Irmgard Merfort
PubMed ID: 18261723
Date Published: 31st Dec 2007
Scales: Cell
Abstract (Expand)
Created: 30th Aug 2012 at 12:33  Last updated: 24th Oct 2013 at 16:23
Authors: Stefan Henrich, Stefan Richter, Rebecca C Wade
PubMed ID: 18061917
Date Published: 7th Dec 2007
Scales: Not specified
Abstract:
Created: 31st Oct 2012 at 14:20  Last updated: 24th Oct 2013 at 16:23
Authors: Thomas Maiwald, Clemens Kreutz, Andrea C Pfeifer, Sebastian Bohl, Ursula Klingmüller, Jens Timmer
PubMed ID: 18033750
Date Published: 24th Nov 2007
Scales: Not specified
Abstract (Expand)
Created: 17th Aug 2012 at 10:21  Last updated: 24th Oct 2013 at 16:23
Authors: Razif R Gabdoulline, Matthias Stein, Rebecca C Wade
PubMed ID: 17919319
Date Published: 5th Oct 2007
Scales: Not specified
Abstract (Expand)
Created: 31st Oct 2012 at 14:14  Last updated: 24th Oct 2013 at 16:23
A computational analysis of protein interactions in metabolic networks reveals novel enzyme pairs potentially involved in metabolic channeling
Authors: Carola Huthmacher, Christoph Gille, Hermann-Georg Holzhütter
PubMed ID: 17988690
Date Published: 5th Oct 2007
Projects: No Projects
Journal: J. Theor. Biol.
Citation: J. Theor. Biol. 252(3): 456-64
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 13:00  Last updated: 24th Oct 2013 at 16:23
Authors: S Hengl, C Kreutz, J Timmer, T Maiwald
PubMed ID: 17660526
Date Published: 28th Jul 2007
Scales: Not specified
Abstract (Expand)
Created: 17th Aug 2012 at 10:25  Last updated: 24th Oct 2013 at 16:23
Authors: Stefan Legewie, Birgit Schoeberl, Nils Blüthgen, Hanspeter Herzel
PubMed ID: 17526574
Date Published: 25th May 2007
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:07  Last updated: 24th Oct 2013 at 16:23
Activation of NF-kappaB by IL-1beta blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human gamma-fibrinogen gene
Authors: Ute Albrecht, Xiangping Yang, Rosanna Asselta, Verena Keitel, Maria Luisa Tenchini, Stephan Ludwig, Peter C Heinrich, Dieter Häussinger, Fred Schaper, Johannes G Bode
PubMed ID: 17543500
Date Published: 1st May 2007
Projects: A1.3: Identification of crucial metabolic processes during hepatocyte pr..., A2.2: Regulation of pro-apoptotic and anti-apoptotic responses in hepato..., A2.4: Linking signalling pathways regulating liver regeneration and orga..., A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato...
Journal: Cell. Signal.
Citation: Cell. Signal. 19(9): 1866-78
Scales: Not specified
Abstract (Expand)
Created: 31st Aug 2012 at 11:47  Last updated: 24th Oct 2013 at 16:23
Authors: Matthias Stein, Razif R Gabdoulline, Rebecca C Wade
PubMed ID: 17395455
Date Published: 28th Mar 2007
Projects: HepatoSys
Journal: Curr. Opin. Struct. Biol.
Citation: Curr. Opin. Struct. Biol. 17(2): 166-72
Scales: Not specified
Abstract (Expand)
Created: 31st Oct 2012 at 14:15  Last updated: 24th Oct 2013 at 16:23
Authors: Sanja Tomić, Branimir Bertosa, Ting Wang, Rebecca C Wade
PubMed ID: 17295314
Date Published: 14th Feb 2007
Scales: Not specified
Abstract (Expand)
Created: 31st Oct 2012 at 14:17  Last updated: 24th Oct 2013 at 16:23
Authors: Lutz Brusch, Perla Del Conte-Zerial, Yannis Kalaidzidis, Jochen Rink, Bianca Habermann, Marino Zerial, Andreas Deutsch
DOI: 10.1007/978-0-8176-4558-8_4
Date Published: 2007
Projects: HepatoSys
Book: Mathematical Modeling of Biological Systems, Volume I
Citation: Modeling and Simulation in Science, Engineering and Technology : 33
Scales: Cell
Abstract (Expand)
Created: 25th Jul 2011 at 17:22  Last updated: 24th Oct 2013 at 16:23
Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways
Authors: U Klingmüller, A Bauer, S Bohl, P J Nickel, K Breitkopf, S Dooley, S Zellmer, C Kern, I Merfort, T Sparna, J Donauer, G Walz, M Geyer, C Kreutz, M Hermes, F Götschel, A Hecht, D Walter, L Egger, K Neubert, C Borner, M Brulport, W Schormann, C Sauer, F Baumann, R Preiss, S MacNelly, P Godoy, E Wiercinska, L Ciuclan, J Edelmann, K Zeilinger, M Heinrich, U M Zanger, R Gebhardt, T Maiwald, R Heinrich, J Timmer, F von Weizsäcker, J G Hengstler
PubMed ID: 17186705
Date Published: 26th Dec 2006
Scales: Cell
Abstract (Expand)
Created: 30th Aug 2012 at 12:39  Last updated: 24th Oct 2013 at 16:24
Authors: Stefan Hoops, Sven Sahle, Ralph Gauges, Christine Lee, Jürgen Pahle, Natalia Simus, Mudita Singhal, Liang Xu, Pedro Mendes, Ursula Kummer
PubMed ID: 17032683
Date Published: 10th Oct 2006
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:26  Last updated: 24th Oct 2013 at 16:24
Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability
Authors: Stefan Legewie, Nils Blüthgen, Hanspeter Herzel
PubMed ID: 16978046
Date Published: 28th Jul 2006
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:08  Last updated: 24th Oct 2013 at 16:24
Authors: Nils Blüthgen, Frank J Bruggeman, Stefan Legewie, Hanspeter Herzel, Hans V Westerhoff, Boris N Kholodenko
PubMed ID: 16478465
Date Published: 16th Feb 2006
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:10  Last updated: 24th Oct 2013 at 16:24
Computational processing and error reduction strategies for standardized quantitative data in biological networks
Authors: Marcel Schilling, Thomas Maiwald, Sebastian Bohl, Markus Kollmann, Clemens Kreutz, Jens Timmer, Ursula Klingmüller
PubMed ID: 16336276
Date Published: 13th Dec 2005
Scales: Not specified
Abstract (Expand)
Created: 23rd Aug 2012 at 13:22  Last updated: 24th Oct 2013 at 16:24
Authors: Stefan Legewie, Nils Blüthgen, Reinhold Schäfer, Hanspeter Herzel
PubMed ID: 16261195
Date Published: 28th Oct 2005
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:11  Last updated: 24th Oct 2013 at 16:24
Authors: Stefan Legewie, Nils Blüthgen, Hanspeter Herzel
PubMed ID: 16098190
Date Published: 16th Aug 2005
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:13  Last updated: 24th Oct 2013 at 16:24
Authors: Kristian Rother, Sabrina Hoffmann, Sascha Bulik, Andreas Hoppe, Johann Gasteiger, Herrmann-Georg Holzhütter
PubMed ID: 20513391
Date Published: 2nd Jun 2010
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: Biophys. J.
Citation: Biophys. J. 98(11): 2478-86
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 10:51  Last updated: 24th Oct 2013 at 16:20
Authors: Andreas Hoppe, Sabrina Hoffmann, Andreas Gerasch, Christoph Gille, Hermann-Georg Holzhütter
PubMed ID: 21255455
Date Published: 22nd Oct 2010
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., A3.4: Linking signalling to metabolic functions
Journal: BMC Bioinformatics
Citation: BMC Bioinformatics 12: 28
Scales: Not specified
Abstract (Expand)
Created: 7th Feb 2011 at 12:27  Last updated: 24th Oct 2013 at 16:19
Authors: Christoph Gille, Katrin Hübner, Andreas Hoppe, Hermann-Georg Holzhütter
PubMed ID: 21824972
Date Published: 8th Aug 2011
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., F2: The Liver Knowledge Base (LKB)
Journal: Bioinformatics
Citation: Bioinformatics 27(19): 2763-4
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 10:45  Last updated: 24th Oct 2013 at 16:18
Authors: Claudio Collinet, Martin Stöter, Charles R Bradshaw, Nikolay Samusik, Jochen C Rink, Denise Kenski, Bianca Habermann, Frank Buchholz, Robert Henschel, Matthias S Mueller, Wolfgang E Nagel, Eugenio Fava, Yannis Kalaidzidis, Marino Zerial
PubMed ID: 20190736
Date Published: 28th Feb 2010
Projects: A1.3: Identification of crucial metabolic processes during hepatocyte pr..., A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato..., A3.5: The impact of cell polarity on metabolism detoxification and endoc..., C2: Organization of the sinusoidal system and the liver lobule - referen..., C5: Structural changes and functional consequences of the liver lobular/..., C6: Organization and function of the sinusoidal system and the liver lob...
Journal: Nature
Citation: Nature 464(7286): 243-9
Scales: Not specified
Abstract (Expand)
Created: 23rd Nov 2012 at 14:04  Last updated: 24th Oct 2013 at 16:20
Authors: Markus Koschorreck, Holger Conzelmann, Sybille Ebert, Michael Ederer, Ernst Dieter Gilles
PubMed ID: 17854494
Date Published: 13th Sep 2007
Projects: No Projects
Journal: BMC Bioinformatics
Citation: BMC Bioinformatics 8: 336
Scales: Not specified
Abstract (Expand)
Created: 30th Oct 2012 at 09:04  Last updated: 24th Oct 2013 at 16:23
Simplification of biochemical models: a general approach based on the analysis of the impact of individual species and reactions on the systems dynamics
Authors: Irina Surovtsova, Natalia Simus, Katrin Hübner, Sven Sahle, Ursula Kummer
PubMed ID: 22390191
Date Published: 5th Mar 2012
Scales: Cell
Abstract (Expand)
Created: 30th Aug 2012 at 13:03  Last updated: 24th Oct 2013 at 16:16
Authors: Nikolay Borisov, Edita Aksamitiene, Anatoly Kiyatkin, Stefan Legewie, Jan Berkhout, Thomas Maiwald, Nikolai P Kaimachnikov, Jens Timmer, Jan B Hoek, Boris N Kholodenko
PubMed ID: 19357636
Date Published: 7th Apr 2009
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 11:41  Last updated: 24th Oct 2013 at 16:21
Authors: Irina Nazarenko, Marcel Jenny, Jana Keil, Cornelia Gieseler, Karen Weisshaupt, Jalid Sehouli, Stefan Legewie, Lena Herbst, Wilko Weichert, Silvia Darb-Esfahani, Manfred Dietel, Reinhold Schäfer, Florian Ueberall, Christine Sers
PubMed ID: 20501645
Date Published: 25th May 2010
Projects: A2.3: Cross-talk and distinct properties of growth factor signalling reg..., B2.1: Hepatic stellate cells as source and target for hepatocellular gro...
Journal: Mol. Cancer Res.
Citation: Mol. Cancer Res. 8(6): 919-34
Scales: Cell
Abstract (Expand)
Created: 11th Sep 2012 at 11:39  Last updated: 24th Oct 2013 at 16:20
Parameter estimation in ordinary differential equations for biochemical processes using the method of multiple shooting
Authors: M Peifer, J Timmer
PubMed ID: 17441551
Date Published: 20th Apr 2007
Scales: Not specified
Abstract (Expand)
Created: 17th Aug 2012 at 10:29  Last updated: 24th Oct 2013 at 16:23
Authors: Kilian Bartholomé, Clemens Kreutz, Jens Timmer
PubMed ID: 19580524
Date Published: 8th Jul 2009
Scales: Cell
Abstract (Expand)
Created: 10th Aug 2012 at 11:44  Last updated: 24th Oct 2013 at 16:21
Authors: Regina Samaga, Axel Von Kamp, Steffen Klamt
PubMed ID: 20078396
Date Published: 19th Jan 2010
Projects: No Projects
Journal: J. Comput. Biol.
Citation: J. Comput. Biol. 17(1): 39-53
Scales: Not specified
Abstract (Expand)
Created: 14th Aug 2012 at 10:31  Last updated: 24th Oct 2013 at 16:20
Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver
Authors: Anne T. Nies, Hermann Koepsell, Stefan Winter, Oliver Burk, Kathrin Klein, Reinhold Kerb, Ulrich M. Zanger, Dietrich Keppler, Matthias Schwab, Elke Schaeffeler
DOI: 10.1002/hep.23103
Date Published: 1st Oct 2009
Projects: A3.4: Linking signalling to metabolic functions
Journal: Hepatology
Citation: Hepatology 50(4) : 1227
Scales: Intercellular
Abstract:
Created: 3rd Aug 2012 at 08:37  Last updated: 24th Oct 2013 at 16:21
Authors: Mara Monetti, Nagarjuna Nagaraj, Kirti Sharma, Matthias Mann
PubMed ID: 21743459
Date Published: 10th Jul 2011
Projects: A1.3: Identification of crucial metabolic processes during hepatocyte pr..., C5: Structural changes and functional consequences of the liver lobular/..., HepatoSys
Journal: Nat. Methods
Citation: Nat. Methods 8(8): 655-8
Scales: Not specified
Abstract (Expand)
Created: 30th Jul 2012 at 13:35  Last updated: 24th Oct 2013 at 16:18
Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis
Authors: Stephan Riedmaier, Kathrin Klein, Stefan Winter, Ute Hofmann, Matthias Schwab, Ulrich M Zanger
PubMed ID: 21852972
Date Published: 27th Jul 2011
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes
Journal: Front Pharmacol
Citation: Front Pharmacol 2: 41
Scales: Cell
Abstract (Expand)
Created: 27th Jun 2012 at 16:05  Last updated: 24th Oct 2013 at 16:18
A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes
Authors: Joachim Bucher, Stephan Riedmaier, Anke Schnabel, Katrin Marcus, Gabriele Vacun, Thomas S Weiss, Wolfgang E Thasler, Andreas K Nüssler, Ulrich M Zanger, Matthias Reuss
PubMed ID: 21548957
Date Published: 6th May 2011
Projects: A3.4: Linking signalling to metabolic functions
Journal: BMC Syst Biol
Citation: BMC Syst Biol 5: 66
Scales: Not specified
Abstract (Expand)
Created: 31st Jan 2012 at 11:59  Last updated: 24th Oct 2013 at 16:18
Authors: Neil Swainston, Martin Golebiewski, Hanan L Messiha, Naglis Malys, Renate Kania, Sylvestre Kengne, Olga Krebs, Saqib Mir, Heidrun Sauer-Danzwith, Kieran Smallbone, Andreas Weidemann, Ulrike Wittig, Douglas B Kell, Pedro Mendes, Wolfgang Müller, Norman W Paton, Isabel Rojas
PubMed ID: 20738395
Date Published: 3rd Aug 2010
Scales: Not specified
Abstract (Expand)
Created: 11th Jan 2011 at 11:11  Last updated: 24th Oct 2013 at 16:20
4-Aminoethylamino-emodin--a novel potent inhibitor of GSK-3beta--acts as an insulin-sensitizer avoiding downstream effects of activated beta-catenin
Authors: Rolf Gebhardt, Katja S Lerche, Frank Götschel, Robert Günther, Jens Kolander, Lars Teich, Sebastian Zellmer, Hans-Jörg Hofmann, Kurt Eger, Andreas Hecht, Frank Gaunitz
PubMed ID: 19228266
Date Published: 3rd Oct 2009
Scales: Intercellular
Abstract (Expand)
Created: 19th Jul 2012 at 14:14  Last updated: 24th Oct 2013 at 16:21
Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes
Authors: A Garten, S Petzold, A Barnikol-Oettler, A Körner, W E Thasler, J Kratzsch, W Kiess, R Gebhardt
PubMed ID: 19912992
Date Published: 11th Nov 2009
Projects: Showcase Steatosis
Journal: Biochem. Biophys. Res. Commun.
Citation: Biochem. Biophys. Res. Commun. 391(1): 376-81
Scales: Cell
Abstract (Expand)
Created: 20th Jul 2012 at 10:11  Last updated: 24th Oct 2013 at 16:21
Organ patterning in the adult stage: the role of Wnt/beta-catenin signaling in liver zonation and beyond
Authors: Rolf Gebhardt, Amalya Hovhannisyan
PubMed ID: 19705440
Date Published: 26th Aug 2009
Projects: C: Liver lobule level, Showcase Steatosis
Journal: Dev. Dyn.
Citation: Dev. Dyn. 239(1): 45-55
Scales: Liver lobule and Liver
Abstract (Expand)
Created: 20th Jul 2012 at 09:49  Last updated: 24th Oct 2013 at 16:21
Authors: Tiago J S Lopes, Tatyana Luganskaja, Maja Vujić Spasić, Matthias W Hentze, Martina U Muckenthaler, Klaus Schümann, Jens G Reich
PubMed ID: 20704761
Date Published: 13th Aug 2010
Projects: B1.3: Linking modulation of iron metabolism with the impact of macrophag...
Journal: BMC Syst Biol
Citation: BMC Syst Biol 4: 112
Scales: Organism
Abstract (Expand)
Created: 19th Jul 2012 at 11:25  Last updated: 24th Oct 2013 at 16:19
An integrative model links multiple inputs and signaling pathways to the onset of DNA synthesis in hepatocytes
Authors: Jérémy Huard, Stephanie Mueller, Ernst D Gilles, Ursula Klingmüller, Steffen Klamt
PubMed ID: 22443451
Date Published: 27th Mar 2012
Projects: A2.3: Cross-talk and distinct properties of growth factor signalling reg..., E1: Integration on the cellular level
Journal: The FEBS journal
Citation: FEBS J. 279(18): 3290-313
Scales: Intercellular
Abstract (Expand)
Created: 18th Jul 2012 at 09:45  Last updated: 24th Oct 2013 at 16:16
Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes
Authors: Sebastian Zellmer, Wolfgang Schmidt-Heck, Patricio Godoy, Honglei Weng, Christoph Meyer, Thomas Lehmann, Titus Sparna, Wiebke Schormann, Seddik Hammad, Clemens Kreutz, Jens Timmer, Fritz von Weizsäcker, Petra A Thürmann, Irmgard Merfort, Reinhard Guthke, Steven Dooley, Jan G Hengstler, Rolf Gebhardt
PubMed ID: 20979052
Date Published: 5th Mar 2010
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: Hepatology
Citation: Hepatology 52(6): 2127-36
Scales: Not specified
Abstract (Expand)
Created: 13th Dec 2010 at 11:21  Last updated: 24th Oct 2013 at 16:20
Authors: Clemens Wrzodek, Adrian Schröder, Andreas Dräger, Dierk Wanke, Kenneth W. Berendzen, Marcel Kronfeld, Klaus Harter, Andreas Zell
DOI: 10.1016/j.biosystems.2009.09.005
Date Published: 2010
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes
Journal: Biosystems
Citation: Biosystems 99(1) : 79
Scales: Not specified
Abstract (Expand)
Created: 27th Jan 2011 at 14:58  Last updated: 24th Oct 2013 at 16:20
Authors: Andreas Dräger, Adrian Schröder, Andreas Zell
DOI: 10.1007/978-1-4419-5797-9_7
Date Published: 2010
Projects: A3.4: Linking signalling to metabolic functions
Book: Systems Biology for Signaling Networks
Citation: Systems Biology for Signaling Networks : 159
Scales: Not specified
Abstract (Expand)
Created: 11th Jul 2011 at 09:40  Last updated: 24th Oct 2013 at 16:20
HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology
Authors: Christoph Gille, Christian Bölling, Andreas Hoppe, Sascha Bulik, Sabrina Hoffmann, Katrin Hübner, Anja Karlstädt, Ramanan Ganeshan, Matthias König, Kristian Rother, Michael Weidlich, Jörn Behre, Herrmann-Georg Holzhütter
PubMed ID: 20823849
Date Published: 30th Dec 2009
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., A1.3: Identification of crucial metabolic processes during hepatocyte pr..., F2: The Liver Knowledge Base (LKB)
Journal: Mol. Syst. Biol.
Citation: Mol. Syst. Biol. 6: 411
Scales: Liver
Abstract (Expand)
Created: 9th Dec 2010 at 13:39  Last updated: 24th Oct 2013 at 16:20
Authors: R Schlatter, H Conzelmann, E D Gilles, O Sawodny, T Sauter
PubMed ID: 19640164
Date Published: 31st Jul 2009
Projects: No Projects
Journal: IET Syst Biol
Citation: IET Syst Biol 3(4): 255-65
Scales: Not specified
Abstract (Expand)
Created: 3rd Dec 2010 at 10:00  Last updated: 24th Oct 2013 at 16:21
Authors: Bernd Binder, Andrean Goede, Nikolaus Berndt, Hermann-Georg Holzhütter
PubMed ID: 20041124
Date Published: 21st Jul 2009
Scales: Not specified
Abstract (Expand)
Created: 4th Feb 2011 at 12:47  Last updated: 24th Oct 2013 at 16:21
Authors: Rebekka Schlatter, Kathrin Schmich, Ima Avalos Vizcarra, Peter Scheurich, Thomas Sauter, Christoph Borner, Michael Ederer, Irmgard Merfort, Oliver Sawodny
PubMed ID: 20011108
Date Published: 2nd Jul 2009
Projects: No Projects
Journal: PLoS Comput. Biol.
Citation: PLoS Comput. Biol. 5(12): e1000595
Scales: Not specified
Abstract (Expand)
Created: 3rd Dec 2010 at 09:59  Last updated: 24th Oct 2013 at 16:21
Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood
Authors: A Raue, C Kreutz, T Maiwald, J Bachmann, M Schilling, U Klingmüller, J Timmer
PubMed ID: 19505944
Date Published: 8th Jun 2009
Projects: A2: Integration of Signalling Pathways in Hepatocellular Response
Journal: Bioinformatics
Citation: Bioinformatics 25(15): 1923-9
Scales: Not specified
Abstract (Expand)
Created: 10th Dec 2010 at 12:16  Last updated: 24th Oct 2013 at 16:21
Authors: Sebastian Zellmer, Stephan Sickinger, Wolfgang Schmidt-Heck, Reinhard Guthke, Rolf Gebhardt
PubMed ID: 19470084
Date Published: 14th May 2009
Projects: No Projects
Journal: J. Anat.
Citation: J. Anat. 215(2): 176-83
Scales: Not specified
Abstract (Expand)
Created: 28th Sep 2010 at 09:25  Last updated: 24th Oct 2013 at 16:21
Modeling system states in liver cells: survival, apoptosis and their modifications in response to viral infection
Authors: Nicole Philippi, Dorothee Walter, Rebekka Schlatter, Karine Ferreira, Michael Ederer, Oliver Sawodny, Jens Timmer, Christoph Borner, Thomas Dandekar
PubMed ID: 19772631
Date Published: 12th May 2009
Projects: No Projects
Journal: BMC Syst Biol
Citation: BMC Syst Biol 3: 97
Scales: Not specified
Abstract (Expand)
Created: 3rd Dec 2010 at 10:01  Last updated: 24th Oct 2013 at 16:21
Authors: Clemens Kreutz, Jens Timmer
PubMed ID: 19215298
Date Published: 14th Feb 2009
Projects: A2: Integration of Signalling Pathways in Hepatocellular Response
Journal: FEBS J.
Citation: FEBS J. 276(4): 923-42
Scales: Not specified
Abstract (Expand)
Created: 10th Dec 2010 at 12:14  Last updated: 24th Oct 2013 at 16:21
Authors: Jochen Supper, Lucía Spangenberg, Hannes Planatscher, Andreas Dräger, Adrian Schröder, Andreas Zell
Date Published: 2009
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes
Journal: BMC Syst Biol
Citation: BMC Syst Biol 3(1) : 67
Scales: Not specified
Abstract (Expand)
Created: 27th Jan 2011 at 14:51  Last updated: 24th Oct 2013 at 16:22
Authors: Perla Del Conte-Zerial, Lutz Brusch, Jochen C Rink, Claudio Collinet, Yannis Kalaidzidis, Marino Zerial, Andreas Deutsch
PubMed ID: 18628746
Date Published: 15th Jul 2008
Scales: Not specified
Abstract (Expand)
Created: 29th Jul 2011 at 16:14  Last updated: 24th Oct 2013 at 16:22
Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage
Authors: Steven Dooley, Jafar Hamzavi, Loredana Ciuclan, Patricio Godoy, Iryna Ilkavets, Sabrina Ehnert, Elke Ueberham, Rolf Gebhardt, Stephan Kanzler, Andreas Geier, Katja Breitkopf, Honglei Weng, Peter R Mertens
PubMed ID: 18602923
Date Published: 15th May 2008
Projects: A3.3: Hepatocyte polarity, HepatoSys
Journal: Gastroenterology
Citation: Gastroenterology 135(2): 642-59
Scales: Not specified
Abstract (Expand)
Created: 24th Feb 2012 at 17:08  Last updated: 24th Oct 2013 at 16:22
Authors: Andreas Weidemann, Stefan Richter, Matthias Stein, Sven Sahle, Ralph Gauges, Razif Gabdoulline, Irina Surovtsova, Nils Semmelrock, Bruno Besson, Isabel Rojas, Rebecca Wade, Ursula Kummer
PubMed ID: 18463116
Date Published: 7th May 2008
Scales: Not specified
Abstract (Expand)
Created: 11th Nov 2010 at 18:27  Last updated: 24th Oct 2013 at 16:22
Authors: C Kreutz, M M Bartolome Rodriguez, T Maiwald, M Seidl, H E Blum, L Mohr, J Timmer
PubMed ID: 17768165
Date Published: 3rd Sep 2007
Projects: A2.5: Integration of insulin and Wnt signalling in hepatocytes
Journal: Bioinformatics
Citation: Bioinformatics 23(20): 2747-53
Scales: Not specified
Abstract (Expand)
Created: 10th Dec 2010 at 12:12  Last updated: 24th Oct 2013 at 16:23
Authors: Kilian Bartholomé, Maria Rius, Katrin Letschert, Daniela Keller, Jens Timmer, Dietrich Keppler
PubMed ID: 17548463
Date Published: 4th Jun 2007
Scales: Not specified
Abstract (Expand)
Created: 25th Jul 2011 at 16:51  Last updated: 24th Oct 2013 at 16:23
Authors: Martin Golebiewski, Saqib Mir, Renate Kania, Olga Krebs, Andreas Weidemann, Ulrike Wittig, Isabel Rojas
DOI: 10.1186/1752-0509-1-S1-P4
Date Published: 2007
Scales: Not specified
Abstract:
Created: 11th Nov 2010 at 18:36  Last updated: 24th Oct 2013 at 16:23
Authors: Isabel Rojas, Martin Golebiewski, Renate Kania, Olga Krebs, Saqib Mir, Andreas Weidemann, Ulrike Wittig
DOI: 10.1186/1752-0509-1-S1-S6
Date Published: 2007
Scales: Not specified
Abstract:
Created: 1st Dec 2010 at 13:43  Last updated: 24th Oct 2013 at 16:23
Authors: Isabel Rojas, Martin Golebiewski, Renate Kania, Olga Krebs, Saqib Mir, Andreas Weidemann, Ulrike Wittig
PubMed ID: 17822389
Date Published: 14th Sep 2007
Projects: F3: Kinetic data handling
Journal: In Silico Biol. (Gedrukt)
Citation: In Silico Biol. (Gedrukt) 7(2 Suppl): S37-44
Scales: Not specified
Abstract (Expand)
Created: 5th Nov 2010 at 15:52  Last updated: 24th Oct 2013 at 16:23
Authors: Ulrike Wittig, Martin Golebiewski, Renate Kania, Olga Krebs, Saqib Mir, Andreas Weidemann, Stefanie Anstein, Jasmin Saric, Isabel Rojas
DOI: 10.1007/11799511_9
Date Published: 2006
Projects: F3: Kinetic data handling
Book: Data Integration in the Life Sciences
Citation: Lecture Notes in Computer Science 4075 : 94
Scales: Not specified
Abstract (Expand)
Created: 26th Jul 2011 at 18:33  Last updated: 24th Oct 2013 at 16:24