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Package_editors Transplantation of stem cell-derived hepatocytes

Assays: No Assays

Scales: Liver

Mesenchymal stem cells are extracted from the tissue by collagenase digestion and enriched by their capacity to grow on plastic surfaces. Enriched cells display distinct mesenchymal surface markers and are capable of multiple lineage differentiation. In the presence of specific growth conditions, the cells adopt functional features of differentiated hepatocytes. After orthotopic transplantation, differentiated human stem cells engraft in the host liver parenchyma of immunocompromized mice. This

Created: 24th Oct 2012 at 10:33

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