Publications

 

Wordprocessing LEMming: A Linear Error Model to Normalize Parallel Quantitative Real-Time PCR (qPCR) Data as an Alternative to Reference Gene Based Methods


Authors: R. Feuer, S. Vlaic, J. Arlt, O. Sawodny, U. Dahmen, U. M. Zanger, M. Thomas

PubMed ID: 26325269

Date Published: 1st Sep 2015

Scales: Cell

Abstract (Expand)

BACKGROUND: Gene expression analysis is an essential part of biological and medical investigations. Quantitative real-time PCR (qPCR) is characterized with excellent sensitivity, dynamic range, ...

Created: 17th Sep 2015 at 10:13


 

Wordprocessing libRoadRunner: A High Performance SBML Simulation and Analysis Library


Authors: Endre T Somogyi, Jean-Marie Bouteiller, James A Glazier, Matthias König, J Kyle Medley, Maciej H Swat, Herbert M Sauro

PubMed ID: 26085503

Date Published: 19th Jun 2015

Projects: No Projects

Journal: Bioinformatics

Citation: Bioinformatics :

Scales: Not specified

Abstract (Expand)

This paper presents libRoadRunner, an extensible, high-performance, cross-platform, open-source software library for the simulation and analysis of models expressed using Systems Biology Markup Language ...

Created: 1st Jul 2015 at 16:00


 

Wordprocessing LigDig: a web server for querying ligand-protein interactions


Authors: J. C. Fuller, M. Martinez, S. Henrich, A. Stank, S. Richter, R. C. Wade

DOI: 10.1093/bioinformatics/btu784

Date Published: 29th Nov 2014

Scales: Cell

Abstract (Expand)

Summary: LigDig is a webserver designed to answer questions that previously required several independent queries to diverse data-sources. It also performs basic manipulations and analyses of the ...

Created: 6th Dec 2014 at 18:03   Last updated: 6th Dec 2014 at 18:07


 

Wordprocessing Liver zonation: Novel aspects of its regulation and its impact on homeostasis


Authors: Rolf Gebhardt, Madlen Matz-Soja

PubMed ID: 25024605

Date Published: 16th Jul 2014

Projects: C3: Zonation of metabolism and its regulation, Virtual Liver

Journal: World J. Gastroenterol.

Citation: World J. Gastroenterol. 20(26): 8491-504

Scales: Cell, Intercellular and Liver lobule

Abstract (Expand)

Liver zonation, the spatial separation of the immense spectrum of different metabolic pathways along the liver sinusoids, is fundamental for proper functioning of this organ. Recent progress in elucidating ...

Created: 26th Jan 2015 at 09:50


 

Wordprocessing Lessons learned from quantitative dynamical modeling in systems biology


Authors: Andreas Raue, Marcel Schilling, Julie Bachmann, Andrew Matteson, Max Schelke, Daniel Kaschek, Sabine Hug, Clemens Kreutz, Brian D Harms, Fabian J Theis, Ursula Klingmüller, Jens Timmer

PubMed ID: 24098642

Date Published: 30th Sep 2013

Scales: Cell

Abstract (Expand)

Due to the high complexity of biological data it is difficult to disentangle cellular processes relying only on intuitive interpretation of measurements. A Systems Biology approach that combines ...

Created: 14th Jan 2014 at 11:35


 

Wordprocessing Low perforin expression of early differentiated HCV-specific CD8+ T cells limits their hepatotoxic potential


Authors: Juandy Jo, Bertram Bengsch, Bianca Seigel, Sibylle J Rau, Julia Schmidt, Emmanuel Bisse, Peter Aichele, Ulrike Aichele, Lars Joeckel, Cathy Royer, Karine Sá Ferreira, Christoph Borner, Thomas F Baumert, Hubert E Blum, Volker Lohmann, Richard Fischer, Robert Thimme

PubMed ID: 22425625

Date Published: 14th Mar 2012

Projects: No Projects

Journal: J. Hepatol.

Citation: J. Hepatol. 57(1): 9-16

Scales: Not specified

Abstract (Expand)

Perforin plays a central role in the immunopathogenesis of different viral infections. However, its role in hepatitis C virus (HCV) infection has not been fully understood. Here, we analyzed two closely ...

Created: 22nd Jan 2014 at 15:20


 

Wordprocessing Likelihood based observability analysis and confidence intervals for predictions of dynamic models


Authors: Clemens Kreutz, Andreas Raue, Jens Timmer

DOI: 10.1186/1752-0509-6-120

Date Published: 2012

Projects: A2: Integration of Signalling Pathways in Hepatocellular Response

Journal: BMC Syst Biol

Citation: BMC Syst Biol 6(1) : 120

Scales: Cell

Abstract:

Not specified

Created: 29th Oct 2012 at 10:26   Last updated: 24th Oct 2013 at 16:17


 

Wordprocessing Large-scale network models of IL-1 and IL-6 signalling and their hepatocellular specification


Authors: Anke Ryll, Regina Samaga, Fred Schaper, Leonidas G Alexopoulos, Steffen Klamt

PubMed ID: 21968890

Date Published: 5th Oct 2011

Scales: Cell

Abstract (Expand)

The pro-inflammatory cytokines interleukin 1 (IL-1) and 6 (IL-6) are crucially involved in the regulation of a multitude of physiological processes, in particular coordinating the immune response upon ...

Created: 8th Nov 2011 at 09:14   Last updated: 24th Oct 2013 at 16:17


 

Wordprocessing Large-scale phosphosite quantification in tissues by a spike-in SILAC method


Authors: Mara Monetti, Nagarjuna Nagaraj, Kirti Sharma, Matthias Mann

PubMed ID: 21743459

Date Published: 10th Jul 2011

Scales: Not specified

Abstract (Expand)

Despite progress in mass spectrometry (MS)-based phosphoproteomics, large-scale in vivo analyses remain challenging. Here we report a 'spike-in' stable-isotope labeling with amino acids in ...

Created: 30th Jul 2012 at 13:35   Last updated: 24th Oct 2013 at 16:18


 

Wordprocessing Lipid analysis by thin-layer chromatography—A review of the current state


Authors: Beate Fuchs, Rosmarie Süß, Kristin Teuber, Mandy Eibisch, Jürgen Schiller

DOI: 10.1016/j.chroma.2010.11.066

Date Published: 1st May 2011

Projects: No Projects

Journal: Journal of Chromatography A

Citation: Journal of Chromatography A 1218(19) : 2754

Scales: Not specified

Abstract (Expand)

High-performance thin-layer chromatography (HPTLC) is a widely used, fast and relatively inexpensive method of separating complex mixtures. It is particularly useful for smaller, apolar compounds and ...

Created: 4th Aug 2012 at 16:19   Last updated: 24th Oct 2013 at 16:18


 

Wordprocessing Lipid analysis by thin-layer chromatography--a review of the current state


Authors: Beate Fuchs, Rosmarie Süss, Kristin Teuber, Mandy Eibisch, Jürgen Schiller

PubMed ID: 21167493

Date Published: 14th Oct 2010

Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...

Journal: J Chromatogr A

Citation: J Chromatogr A 1218(19): 2754-74

Scales: Not specified

Abstract (Expand)

High-performance thin-layer chromatography (HPTLC) is a widely used, fast and relatively inexpensive method of separating complex mixtures. It is particularly useful for smaller, apolar compounds and ...

Created: 23rd Jun 2011 at 17:18   Last updated: 24th Oct 2013 at 16:19



Log in / Register

Need an account?
Sign up

Forgotten password?

Front Page

Virtual Liver Network

(v.0.22.0)

Related Projects and friends


Imprint Taverna workflow workbench myExperiment JWS Online ISATAB myGrid Sabio-RK BioPortal Semantic SBML

Powered by:

Ror-logo-32

Icons:
Silk icons 1.3
Crystal Clear icons