Wordprocessing KEGGViewer, a BioJS component to visualize KEGG Pathways

Authors: Jose M Villaveces, Rafael C Jimenez, Bianca H Habermann

PubMed ID: 24715980

Date Published: 13th Feb 2014

Projects: No Projects

Journal: F1000Res

Citation: F1000Res 3: 43

Scales: Not specified

Abstract (Expand)

Signaling pathways provide essential information on complex regulatory processes within the cell. They are moreover widely used to interpret and integrate data from large-scale studies, such as expression ...

Created: 11th Aug 2014 at 16:29


Wordprocessing Kinetic Modeling of Human Hepatic Glucose Metabolism in T2DM Predicts Higher Risk of Hypoglycemic Events in Rigorous Insulin Therapy

Authors: M. Koenig, H.-G. Holzhuetter

DOI: 10.1074/jbc.M112.382069

Date Published: 12th Sep 2012

Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., A1: Cellular metabolism, A3.4: Linking signalling to metabolic functions

Journal: Journal of Biological Chemistry

Citation: Journal of Biological Chemistry 287(44) : 36978

Scales: Cell and Liver

Abstract (Expand)

A major problem in the insulin therapy of patients with diabetes type 2 (T2DM) is the increased occurrence of hypoglycemic events which, if left untreated, may cause confusion or fainting and in severe ...

Created: 4th Oct 2012 at 18:18   Last updated: 24th Oct 2013 at 16:15


Wordprocessing Kinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reactive Oxygen Species

Authors: Nikolaus Berndt, Sascha Bulik, Hermann-Georg Holzhütter

PubMed ID: 22719765

Date Published: 10th Jun 2012

Projects: A1: Cellular metabolism

Journal: Int J Cell Biol

Citation: Int J Cell Biol 2012: 757594

Scales: Not specified

Abstract (Expand)

Reduced activity of brain α-ketoglutarate dehydrogenase complex (KGDHC) occurs in a number of neurodegenerative diseases like Parkinson's disease and Alzheimer's disease. In order to quantify ...

Created: 18th Jul 2012 at 10:01   Last updated: 24th Oct 2013 at 16:16


Wordprocessing KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats

Authors: Clemens Wrzodek, Andreas Dräger, Andreas Zell

PubMed ID: 21700675

Date Published: 25th Jun 2011

Scales: Cell and Intercellular

Abstract (Expand)

SUMMARY: The KEGG PATHWAY database provides a widely used service for metabolic and non-metabolic pathways. It contains manually drawn pathway maps with information about the genes, reactions and ...

Created: 30th Jun 2011 at 08:35   Last updated: 24th Oct 2013 at 16:18


Wordprocessing Kinetic hybrid models composed of mechanistic and simplified enzymatic rate laws--a promising method for speeding up the kinetic modelling of complex metabolic networks

Authors: Sascha Bulik, Sergio Grimbs, Carola Huthmacher, Joachim Selbig, Hermann G Holzhütter

PubMed ID: 19137631

Date Published: 13th Jan 2009

Projects: No Projects

Journal: FEBS J.

Citation: FEBS J. 276(2): 410-24

Scales: Not specified

Abstract (Expand)

Kinetic modelling of complex metabolic networks - a central goal of computational systems biology - is currently hampered by the lack of reliable rate equations for the majority of the underlying ...

Created: 4th Jan 2013 at 11:06   Last updated: 24th Oct 2013 at 16:22


Wordprocessing Kinetic mechanisms for overexpression insensitivity and oncogene cooperation

Authors: Stefan Legewie, Christine Sers, Hanspeter Herzel

PubMed ID: 19059249

Date Published: 4th Dec 2008

Projects: HepatoSys

Journal: FEBS Lett.

Citation: FEBS Lett. 583(1): 93-6

Scales: Not specified

Abstract (Expand)

Minor (5-10 fold) activation of mitogenic signalling cascades typically induces cell division upon extracellular stimulation and is sufficient to support tumourigenesis when permanently triggered by ...

Created: 11th Sep 2012 at 12:56   Last updated: 24th Oct 2013 at 16:22

Log in / Register

Need an account?
Sign up

Forgotten password?

Front Page

Virtual Liver Network


Related Projects and friends

Imprint Taverna workflow workbench myExperiment JWS Online ISATAB myGrid Sabio-RK BioPortal Semantic SBML

Powered by:


Silk icons 1.3
Crystal Clear icons

Virtual Liver Seek uses one essential cookie to keep you session open and one cookie to keep your consent.

By continuing to use this site you agree to the use of cookies