Wordprocessing 4-Aminoethylamino-emodin--a novel potent inhibitor of GSK-3beta--acts as an insulin-sensitizer avoiding downstream effects of activated beta-catenin

Authors: Rolf Gebhardt, Katja S Lerche, Frank Götschel, Robert Günther, Jens Kolander, Lars Teich, Sebastian Zellmer, Hans-Jörg Hofmann, Kurt Eger, Andreas Hecht, Frank Gaunitz

PubMed ID: 19228266

Date Published: 3rd Oct 2009

Projects: HepatoSys

Journal: J. Cell. Mol. Med.

Citation: J. Cell. Mol. Med. 14(6A): 1276-93

Scales: Intercellular

Abstract (Expand)

Glycogen synthase kinase-3beta (GSK-3beta) is a key target and effector of downstream insulin signalling. Using comparative protein kinase assays and molecular docking studies we characterize the ...

Created: 19th Jul 2012 at 14:14   Last updated: 24th Oct 2013 at 16:21

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