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The interaction properties of the human Rab GTPase family--comparative analysis reveals determinants of molecular binding selectivity

Abstract:

Rab GTPases constitute the largest subfamily of the Ras protein superfamily. Rab proteins regulate organelle biogenesis and transport, and display distinct binding preferences for effector and activator proteins, many of which have not been elucidated yet. The underlying molecular recognition motifs, binding partner preferences and selectivities are not well understood.

22523562

Projects: A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato...

PLoS ONE
PLoS ONE 7(4): e34870
16th Apr 2012

Matthias Stein, Manohar Pilli, Sabine Bernauer, Bianca H Habermann, Marino Zerial, Rebecca C Wade

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[Bianca Habermann] [Marino Zerial] [Rebecca Wade]

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Cell
Views: 2140
  • Created: 19th Jul 2012 at 09:45
  • Last updated: 24th Oct 2013 at 16:16

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