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Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels

Abstract:

Hedgehog signaling plays an important role in embryonic development, organogenesis and cancer. In the adult liver, Hedgehog signaling in non-parenchymal cells has been found to play a role in certain disease states such as fibrosis and cirrhosis. However, whether the Hedgehog pathway is active in mature healthy hepatocytes and is of significance to liver function are controversial.

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Projects: Virtual Liver

Cell Commun. Signal
Cell Commun. Signal 12(1): 11
18th Feb 2014

Madlen Matz-Soja, Susanne Aleithe, Eugenia Marbach, Jan Böttger, Katrin Arnold, Wolfgang Schmidt-Heck, Jürgen Kratzsch, Rolf Gebhardt

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[Madlen Matz-Soja] [Susanne Aleithe] [Eugenia Marbach] [Jan Böttger] [Katrin Arnold]
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Views: 1566
  • Created: 11th Mar 2014 at 14:51

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