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Metannogen: annotation of biological reaction networks

Created: 4th Jan 2013 at 10:45
Last updated: 24th Oct 2013 at 16:18

Abstract:

Semantic annotations of the biochemical entities constituting a biological reaction network are indispensable to create biologically meaningful networks. They further heighten efficient exchange, reuse and merging of existing models which concern present-day systems biology research more often. Two types of tools for the reconstruction of biological networks currently exist: (i) several sophisticated programs support graphical network editing and visualization. (ii) Data management systems permit reconstruction and curation of huge networks in a team of scientists including data integration, annotation and cross-referencing. We seeked ways to combine the advantages of both approaches.

PubMed ID: 21824972

Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., F2: The Liver Knowledge Base (LKB)

Journal: Bioinformatics
Citation: Bioinformatics 27(19): 2763-4
Date Published: 8th Aug 2011

Authors: Christoph Gille, Katrin Hübner, Andreas Hoppe, Hermann-Georg Holzhütter

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