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Dynamical modeling and multi-experiment fitting with PottersWheel

Abstract:

Modelers in Systems Biology need a flexible framework that allows them to easily create new dynamic models, investigate their properties and fit several experimental datasets simultaneously. Multi-experiment-fitting is a powerful approach to estimate parameter values, to check the validity of a given model, and to discriminate competing model hypotheses. It requires high-performance integration of ordinary differential equations and robust optimization.

18614583

Projects: HepatoSys

Bioinformatics
Bioinformatics 24(18): 2037-43
9th Jul 2008

Thomas Maiwald, Jens Timmer

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[Thomas Maiwald] [Jens Timmer]

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Views: 1593
  • Created: 17th Aug 2012 at 10:13
  • Last updated: 24th Oct 2013 at 16:22

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