Kformula Response of hepatocytes to rapid change in the medium composition (gene regulatory network): Model 1100 freshMedia

Uploader: Data From HepatoSys

Contributor: Data From HepatoSys, Reinhard Guthke, Rolf Gebhardt, Sebastian Zellmer, Wolfgang Schmidt-Heck

Other contributors: Not specified

Model type: Not specified

Model format: SBML

Version: 1

Projects: HepatoSys

Organism: Mus musculus

Environment: Not specified

Scales: Cell

Primary hepatocytes were exposed to a stimulus by exchanging culture medium, thereby simulating changes in the blood composition. The expression of genes at different time points was recorded. Differentially expressed genes were clustered using fuzzy c-means algorithm into five groups. The arcs of the possible network were identified using the NetGenerator algorithm under the restriction of biological knowledge. The analysis was restricted to the main metabolic pathways of hepatocytes. The reverse

Created: 25th Jul 2011 at 14:48   Last updated: 24th Feb 2012 at 15:11

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