Flask3-64x64 Fluidigm dynamic arrays for TaqMan® PCR

ID: 32

Assay type: Transcriptional profiling

Technology type: fluidigm high-throughput taqman platform

Investigation: 1 hidden item

Study: 1 hidden item

Contributor: Maria Thomas

Projects: A3.4: Linking signalling to metabolic functions, Showcase Steatosis

Homo sapiens : [Hepatocyte] (primary cell culture)

SOPs: 2 hidden items

Data files: 5 hidden items

Scales: Not specified

A technology which offers on-chip networks of microfluidc channels.This platform enables us to perform high-throughput real-time PCR with up to 9.216 data points in one run in TaqMan data quality.

Created: 6th Nov 2012 at 06:47   Last updated: 24th Jul 2015 at 12:18


Desktop From Hepatocytes to Whole Liver Function: A Multi-Scale Model of Human Hepatic Galactose Metabolism

ID: 71

Biological problem addressed: Metabolic network

Investigation: Investigation: Multi-scale model galactose meta...

Study: Study : Galactose metabolism in the liver

Models: 2 hidden items

Scales: Cell, Liver lobule and Liver

We present a multi-scale model of liver galactose metabolism bridging the scales from single-cell metabolism over the tissue level to the whole-organ. The model combines a detailed kinetic model of the cellular galactose metabolism with a tissue-scale perfusion model of the sinusoid. The metabolic capacity of the whole liver is modelled by integrating the heterogeneous contribution of sinusoids differing in blood-flow rates and tissue-architecture. The model was applied to the normal physiological

Created: 3rd Nov 2013 at 15:17   Last updated: 24th Jul 2015 at 13:30

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