Biological problem addressed 'Gene expression'

Parents Modelling Analysis
Current Biological problem addressed Gene expression
Children No child terms

Related assays


Desktop Response of hepatocytes to rapid change in the medium composition (gene regulatory network)

Contributor: Data From HepatoSys

Projects: HepatoSys

Mus musculus : C57BL/6N (wild-type / wild-type) : [Hepatocyte] (primary cell culture)


Data files: Dynamic network reconstruction identified unexp...

Scales: Cell

Primary hepatocytes were exposed to a stimulus by exchanging culture medium, thereby simulating changes in the blood composition. The expression of genes at different time points was recorded. Differentially expressed genes were clustered using fuzzy c-means algorithm into five groups. The arcs of the possible network were identified using the NetGenerator algorithm under the restriction of biological knowledge. The analysis was restricted to the main metabolic pathways of hepatocytes. The reverse

Created: 1st Aug 2011 at 15:44   Last updated: 24th Jul 2015 at 11:50

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