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Package_editors In vivo Rab5 knock down


Assays: In vivo LNP injections

Scales: Cell, Intercellular and Liver

No description specified

Created: 28th Feb 2014 at 12:38   Last updated: 11th Jan 2016 at 15:18


 

Package_editors In vitro knock down of Rab5


Assays: In vitro knock down of Rab5

Scales: Not specified

No description specified

Created: 28th Feb 2014 at 11:08   Last updated: 11th Jan 2016 at 15:18


 

Package_editors Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape



 

Package_editors Study: Glucose metabolism in the liver


Assays: Kinetic modelling of hepatic glucose metabolism

Scales: Liver

No description specified

Created: 3rd Nov 2013 at 16:40


 

Package_editors Study : Galactose metabolism in the liver


Assays: From Hepatocytes to Whole Liver Function: A Multi-Scale Model of Human ...

Scales: Cell, Liver lobule and Liver

No description specified

Created: 3rd Nov 2013 at 15:12   Last updated: 3rd Nov 2013 at 15:55


 

Package_editors Integration of intracellular signaling pathways


Projects: E1: Integration on the cellular level

Contributor: Katrin Kolczyk

Assays: No Assays

Scales: Cell

No description specified

Created: 2nd Mar 2011 at 10:39   Last updated: 19th Nov 2012 at 14:12


 

Package_editors Transplantation of stem cell-derived hepatocytes


Assays: No Assays

Scales: Liver

Mesenchymal stem cells are extracted from the tissue by collagenase digestion and enriched by their capacity to grow on plastic surfaces. Enriched cells display distinct mesenchymal surface markers and are capable of multiple lineage differentiation. In the presence of specific growth conditions, the cells adopt functional features of differentiated hepatocytes. After orthotopic transplantation, differentiated human stem cells engraft in the host liver parenchyma of immunocompromized mice. This
...

Created: 24th Oct 2012 at 10:33


 

Package_editors Response of hepatocytes to rapid change in the medium composition


ID: 9

Investigation: Exchanging culture medium

Projects: HepatoSys

Contributor: Data From HepatoSys

Assays: Response of hepatocytes to rapid change in the medium composition (gene ..., Response of hepatocytes to rapid change in the medium composition (gene ...

Scales: Not specified

Primary hepatocytes were exposed to a stimulus by exchanging culture medium, thereby simulating changes in the blood composition. The expression of genes at different time points was recorded. Differentially expressed genes were clustered using fuzzy c-means algorithm into five groups. The arcs of the possible network were identified using the NetGenerator algorithm under the restriction of biological knowledge. The analysis was restricted to the main metabolic pathways of hepatocytes. The reverse
...

Created: 1st Aug 2011 at 13:50   Last updated: 1st Aug 2011 at 13:56



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