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Pdf GTC Bio - Protein-protein interaction October 23rd-25th Invited talk


Uploader: Jonathan Fuller

Contributor: Jonathan Fuller

Other contributors: Not specified

Version: 1

Projects: No Projects

Scales: Not specified

Invited talk abstract:

Recent successes have challenged the widely held belief that protein-protein interactions (PPIs) are 'undruggable'. We show that binding pockets defining PPIs and those that define protein-ligand interactions of currently marketed drugs are markedly different. In the case of PPIs, drug discovery methods that simultaneously target several small pockets at the protein-protein interface are likely to increase the chances of success in this new and important field of therapeutics.
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Created: 18th Dec 2013 at 12:40



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