Models

 

Kformula Mathematical model for liver size regulation by N. Hohmann, W. Weiwei, U. Dahmen, O. Dirsch, A. Deutsch, A. Voss-Böhme


Uploader: Lutz Brusch

Contributor: Andreas Deutsch, Anja Voß–Böhme, Nadine Hohmann, Olaf Dirsch, Uta Dahmen, Weiwei Wei

Other contributors: Not specified

Model type: Not specified

Model format: Not specified

Scales: Liver lobule and Liver

Model has been published in Hohmann et al., PLoS ONE 9(4): e93207 (2014), doi: 10.1371/journal.pone.0093207

Created: 24th Jan 2014 at 14:33   Last updated: 17th Jun 2014 at 11:42


 

Kformula Mobi PBPK Models of Paracetamol, Ammonia and Allopurinol


Uploader: Markus Krauß

Contributor: Jörg Lippert, Lars Küpfer, Markus Krauß

Other contributors: Not specified

Model type: Ordinary differential equations (ODE)

Model format: SXML

Version: 1

Projects: E4: Vertical integration across biological scales, E: Model integration

Organism: Homo sapiens

Environment: MoBi

Scales: Organism

Mobi PBPK Models of Paracetamol, Ammonia and Allopurinol, relating to Publication Krauss et al (2012) in PLoS Comp Biol

Created: 30th Oct 2012 at 09:09   Last updated: 6th May 2015 at 08:07


 

Kformula Model TCA, electrophysiological transmembran potential & respiratory chain


Uploader: Sascha Bulik

Contributor: Hermann-Georg Holzhütter, Nikolaus Berndt, Sascha Bulik

Other contributors: Not specified

Model type: Ordinary differential equations (ODE)

Model format: Not specified

Version: 1

Projects: A1: Cellular metabolism

Organism: Homo sapiens

Environment: Not specified

Scales: Cell

The model comprises the reactions of the citric acid cycle, the respiratory chain, oxidative phosphorylation, mitochondrial ATP generation, the exchange of adenine nucleotides exchange between mitochondrial matrix and cytosol, as well as the transport of small ions across the inner mitochondrial membrane.
The respiratory chain complexes I and III are modelled in high resolution providing insight into electron occupation states of ROS generating sites depending on energetic challenge and enzyme
...

Created: 5th Nov 2012 at 09:45   Last updated: 5th Nov 2012 at 09:45


 

Kformula Morpheus model of Smo regulation in response to Hh


Uploader: Lutz Brusch

Contributor: Lutz Brusch

Other contributors: Not specified

Model type: Ordinary differential equations (ODE)

Model format: Not specified

Version: 1

Projects: A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato...

Organism: Not specified

Environment: Not specified

Scales: Cell

Morpheus model of Smo regulation in response to Hh

As used in refereence:
A.P. Kupinski, I. Raabe, M. Michel, D. Ail, L. Brusch, T. Weidemann, C. Bökel (2013) Phosphorylation of the Smo tail is controlled by membrane localization and is dispensable for clustering, J. Cell Sci., 126, 20, 4684-4697 doi: 10.1242/​jcs.128926

Created: 28th Jan 2014 at 10:17   Last updated: 28th Jan 2014 at 10:18


 

Kformula Morpheus: modeling environment for multicellular systems biology


Uploader: Walter De Back

Contributor: Andreas Deutsch, Lutz Brusch, Walter De Back

Other contributors: Not specified

Model type: Not specified

Model format: Not specified

Scales: Cell, Intercellular and Liver lobule

Morpheus is the modeling environment for multicellular systems biology developed at the IMC group (prof. Andreas Deutsch) at the Center for High Performance Computing at the the Technische Universität Dresden.

See: http://imc.zih.tu-dresden.de/wiki/morpheus

Created: 23rd Oct 2012 at 13:08   Last updated: 4th Dec 2012 at 13:35


 

Kformula MW-AA_version12_abbau


Uploader: Data From HepatoSys

Contributor: Data From HepatoSys, Reinhard Guthke, Rolf Gebhardt, Sebastian Zellmer, Wolfgang Schmidt-Heck

Other contributors: Not specified

Model type: Not specified

Model format: SBML

Version: 1

Projects: HepatoSys

Organism: Mus musculus

Environment: Not specified

Scales: Cell

Aminosäure-Abbau in primären Maushepatozyten

Created: 1st Aug 2011 at 12:16   Last updated: 24th Feb 2012 at 15:25



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