Models

 

Kformula hepatoModel (stoichiometric model of the hepatocyte metabolism) L2V1


Uploader: Data From HepatoSys

Contributor: Andreas Hoppe, Christian Bölling, Data From HepatoSys, Hermann-Georg Holzhütter, Matthias König, Michael Weidlich, Sascha Bulik

Other contributors: Sabrina Hoffmann, Katrin Hübner, Anja Karlstädt, Ramanan Ganeshan, Kristian Rother, Jörn Behre

Model type: Stoichiometric model

Model format: SBML

Version: 1

Projects: HepatoSys

Organism: Homo sapiens

Environment: Not specified

Scales: Cell

This xml contains the current stoichiometric model on the 6th of november 2008. It is a subnetwork of hepatoNet where all blocked reactions (with respect to our simulation conditions) are removed. This model is ready to use, fulfills already 80% of the hepatocyte functions we intend to include in our model. However, LDL synthesis is not yet realized in this version. We use our proper Identifiers, so if you need a mapping to public ones (e.g. KEGG), contact us.

Created: 27th Jul 2011 at 16:44   Last updated: 24th Feb 2012 at 15:06


 

Kformula hepatoNet (stoichiometric network of the hepatocyte metabolism) L2V3


Uploader: Data From HepatoSys

Contributor: Andreas Hoppe, Christian Bölling, Data From HepatoSys, Hermann-Georg Holzhütter, Matthias König, Michael Weidlich, Sascha Bulik

Other contributors: Sabrina Hoffmann, Katrin Hübner, Anja Karlstädt, Ramanan Ganeshan, Kristian Rother, Jörn Behre

Model type: Stoichiometric model

Model format: SBML

Version: 1

Projects: HepatoSys

Organism: Homo sapiens

Environment: Not specified

Scales: Cell

This xml contains the current stoichiometric network on the 6th of november 2008. It contains all reactions we found to exist in liver until now. We use our proper Identifiers, so if you need a mapping to public ones (e.g. KEGG), contact us.

Created: 27th Jul 2011 at 17:10   Last updated: 24th Feb 2012 at 15:09


 

Kformula HepatoNet 1b with mouse gene annotations


Uploader: Andreas Hoppe

Contributor: Andreas Hoppe, Hermann-Georg Holzhütter

Other contributors: Not specified

Model type: Stoichiometric model

Model format: SBML

Version: 1

Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...

Organism: Mus musculus

Environment: Not specified

Scales: Cell

No description specified

Created: 11th Feb 2013 at 14:44


 

Kformula HepatoNet1 annotated


Uploader: Andreas Dräger

Contributor: Andreas Dräger, Roland Keller, Stephanie Hoffmann

Other contributors: Not specified

Model type: Stoichiometric model

Model format: SBML

Version: 1

Projects: A1: Cellular metabolism

Organism: Homo sapiens

Environment: Not specified

Scales: Cell

This is HepatoNet1 including MIRIAM annotations.

Created: 23rd Mar 2012 at 11:41   Last updated: 12th Jan 2016 at 08:13


 

Kformula Human Geometric Liver Model


Uploader: Lars Ole Schwen

Contributor: Lars Ole Schwen

Other contributors: Not specified

Model type: Not specified

Model format: Not specified

Version: 1

Projects: No Projects

Organism: Homo sapiens

Environment: Not specified

Scales: Liver

supplementary information for L. O. Schwen, A. Schenk, C. Kreutz, J. Timmer, M. M. Bartolomé-Rodriguez, L. Kuepfer, and T. Preusser: Representative Sinusoids For Hepatic Four-Scale Pharmacokinetics Simulations, PLoS ONE, 10(7):e0133653, 1-39, 2015, DOI 10.1371/journal.pone.0133653

Created: 30th Jul 2015 at 09:25



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